A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of this work is the invention of “borono-sclareolide”, a terpenyl radical precursor that enables gram-scale preparation of (+)-chromazonarol. Subsequent synthetic operations on this key intermediate permit rapid access to a variety of related meroterpenoids, many of which possess important biological activity
The bicyclo[3.3.1]nonane architecture is a privileged structural motif found in over 1000 natural pr...
© 2020 Elsevier B.V. Current developments in the pharmaceutical industry indicate an increase in att...
(+)-Hongoquercin A and B were synthesized from commercially available trans,trans-farnesol in six an...
A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of t...
A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of t...
Meroterpenoids are mixed terpenoid–polyketide natural products with a variety of biological activiti...
Synthetic efforts towards various meroterpenoid natural products based on biosynthetic speculation w...
Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking...
Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking...
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. In the last decade, the chemistry of merot...
Meroterpenoids belong to a class of natural products that are biosynthesised via a mixed polyketide-...
The efficient synthesis and antifungal exploration of (+)-yahazunol and related natural products are...
This thesis outlines synthetic efforts towards three different natural product families. Norascyrono...
Total synthesis of the Rhododendron meroterpenoids rubiginosins A and G, which both contain unusual ...
3,5-Dimethylorsellinic acid (DMOA)-derived meroterpenoids are a rich, structurally diverse family of...
The bicyclo[3.3.1]nonane architecture is a privileged structural motif found in over 1000 natural pr...
© 2020 Elsevier B.V. Current developments in the pharmaceutical industry indicate an increase in att...
(+)-Hongoquercin A and B were synthesized from commercially available trans,trans-farnesol in six an...
A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of t...
A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of t...
Meroterpenoids are mixed terpenoid–polyketide natural products with a variety of biological activiti...
Synthetic efforts towards various meroterpenoid natural products based on biosynthetic speculation w...
Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking...
Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking...
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. In the last decade, the chemistry of merot...
Meroterpenoids belong to a class of natural products that are biosynthesised via a mixed polyketide-...
The efficient synthesis and antifungal exploration of (+)-yahazunol and related natural products are...
This thesis outlines synthetic efforts towards three different natural product families. Norascyrono...
Total synthesis of the Rhododendron meroterpenoids rubiginosins A and G, which both contain unusual ...
3,5-Dimethylorsellinic acid (DMOA)-derived meroterpenoids are a rich, structurally diverse family of...
The bicyclo[3.3.1]nonane architecture is a privileged structural motif found in over 1000 natural pr...
© 2020 Elsevier B.V. Current developments in the pharmaceutical industry indicate an increase in att...
(+)-Hongoquercin A and B were synthesized from commercially available trans,trans-farnesol in six an...